HTLV1 Target gene Detail Information

> FKBP15 Gene Search Result


Gene Information
Gene Name FKBP15
Gene ID 23307
Gene Full Name FKBP prolyl isomerase 15
Gene Alias FKBP133; PPP1R76; KIAA0674
Transcripts ENSG00000119321
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoli;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5T1M5
HGNC ID HGNC:23397
VEGA ID OTTHUMG00000020518
OMIM ID 617398
String ID 9606.ENSP00000238256
PharmGKB ID PA162388608
Target gene [FKBP15] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000043 chr9 3417 2229 1395 7041 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of FKBP15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FKBP15 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of FKBP15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FKBP15 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).