Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> FKBP5 Gene Search Result


Gene Information
Gene Name FKBP5
Gene ID 2289
Gene Full Name FKBP prolyl isomerase 5
Gene Alias P54; AIG6; FKBP51; FKBP54; PPIase; Ptg-10
Transcripts ENSG00000096060
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q13451
HGNC ID HGNC:3721
VEGA ID OTTHUMG00000014576
OMIM ID 602623
String ID 9606.ENSP00000444810
PharmGKB ID PA28162
Target gene [FKBP5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004355 chr6 76 8 84 View
1011507 chr6 3 6 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of FKBP5 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FKBP5 expression: Low -> High
Lollipop of FKBP5 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of FKBP5 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FKBP5 expression and immune infiltrating cell level correlation result in HBV+ samples
FKBP5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).