HBV Target gene Detail Information

> FLNB Gene Search Result

Gene Information

Gene Name	FLNB
Gene ID	2317
Gene Full Name	filamin B
Gene Alias	AOI; FH1; SCT; TAP; LRS1; TABP; FLN-B; FLN1L; ABP-278; ABP-280
Transcripts	ENSG00000136068
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Actin filaments;Cytosol;Golgi apparatus;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O75369
HGNC ID	HGNC:3755
VEGA ID	OTTHUMG00000159158
OMIM ID	603381
String ID	9606.ENSP00000420213
PharmGKB ID	PA28173

Target gene [FLNB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002157	chr3	213	56	57	326	View
1003221	chr3	111	14	30	155	View
1009121	chr3	13	4		17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FLNB expression and immune infiltrating cell level correlation result in HBV+ samples
FLNB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).