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HBV Target gene Detail Information

> FNDC3B Gene Search Result


Gene Information
Gene Name FNDC3B
Gene ID 64778
Gene Full Name fibronectin type III domain containing 3B
Gene Alias FAD104; PRO4979; YVTM2421
Transcripts ENSG00000075420
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Gene Function Oncogene
Uniport_ID Q53EP0
HGNC ID HGNC:24670
VEGA ID OTTHUMG00000156761
OMIM ID 611909
String ID 9606.ENSP00000338523
PharmGKB ID PA134936830
Target gene [FNDC3B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004978 chr3 49 15 1 65 View
1012451 chr3 2 5 7 View
1017256 chr3 1 1 View
1400099 chr3 1 2 16 19 View
1404302 chr3 5 5 View
1404616 chr3 59 4 63 View
1404953 chr3 332 18 2 352 View
1404995 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of FNDC3B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FNDC3B expression: Low -> High
Lollipop of FNDC3B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of FNDC3B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FNDC3B expression and immune infiltrating cell level correlation result in HBV+ samples
FNDC3B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).