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HBV Target gene Detail Information

> FXYD1 Gene Search Result


Gene Information
Gene Name FXYD1
Gene ID 5348
Gene Full Name FXYD domain containing ion transport regulator 1
Gene Alias PLM
Transcripts ENSG00000266964
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Nucleoli;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID O00168
HGNC ID HGNC:4025
VEGA ID OTTHUMG00000182359
OMIM ID 602359
String ID 9606.ENSP00000481244
PharmGKB ID PA28441
Target gene [FXYD1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003012 chr19 103 27 46 176 View
1403705 chr19 103 27 46 176 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of FXYD1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FXYD1 expression: Low -> High
Lollipop of FXYD1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of FXYD1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FXYD1 expression and immune infiltrating cell level correlation result in HBV+ samples
FXYD1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).