HPV Target gene Detail Information

> GNRHR Gene Search Result

Gene Information

Gene Name	GNRHR
Gene ID	2798
Gene Full Name	gonadotropin releasing hormone receptor
Gene Alias	HH7; GRHR; LRHR; LHRHR; GNRHR1
Transcripts	ENSG00000109163
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID	P30968
HGNC ID	HGNC:4421
VEGA ID	OTTHUMG00000129302
OMIM ID	138850
String ID	9606.ENSP00000226413
Drugbank ID	BE0000203
PharmGKB ID	PA28800

Target gene [GNRHR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402098	chr4	109	63	33	205	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of GNRHR expression and immune infiltrating cell level correlation result in HPV+ samples
GNRHR expression: Low -> High

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of GNRHR expression and immune infiltrating cell level correlation result in HPV+ samples
GNRHR expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of GNRHR expression and immune infiltrating cell level correlation result in HPV+ samples
GNRHR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).