HIV Target gene Detail Information

> GTF2H1 Gene Search Result

Gene Information

Gene Name	GTF2H1
Gene ID	2965
Gene Full Name	general transcription factor IIH subunit 1
Gene Alias	P62; BTF2; TFB1; TFIIH
Transcripts	ENSG00000288114
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	P32780
HGNC ID	HGNC:4655
VEGA ID	OTTHUMG00000167690
OMIM ID	189972
String ID	9606.ENSP00000265963
PharmGKB ID	PA29041

Target gene [GTF2H1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007371	chr11	19			19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GTF2H1 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2H1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GTF2H1 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2H1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).