HBV Target gene Detail Information

> HTR3B Gene Search Result

Gene Information

Gene Name	HTR3B
Gene ID	9177
Gene Full Name	5-hydroxytryptamine receptor 3B
Gene Alias	5-HT3B
Transcripts	ENSG00000149305
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O95264
HGNC ID	HGNC:5298
VEGA ID	OTTHUMG00000168210
OMIM ID	604654
String ID	9606.ENSP00000260191
Drugbank ID	BE0004817
PharmGKB ID	PA29556

Target gene [HTR3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007398	chr11	26	1		27	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of HTR3B expression and immune infiltrating cell level correlation result in HBV+ samples
HTR3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).