HTLV1 Target gene Detail Information

> IDO2 Gene Search Result

Gene Information

Gene Name	IDO2
Gene ID	169355
Gene Full Name	indoleamine 2,3-dioxygenase 2
Gene Alias	INDOL1
Transcripts	ENSG00000188676
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6ZQW0
HGNC ID	HGNC:27269
VEGA ID	OTTHUMG00000141271
OMIM ID	612129
String ID	9606.ENSP00000443432
PharmGKB ID	PA164720782

Target gene [IDO2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009386	chr8	37			37	View
6012169	chr8	11	11	1	23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of IDO2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
IDO2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).