HBV Target gene Detail Information

> IKZF2 Gene Search Result

Gene Information

Gene Name	IKZF2
Gene ID	22807
Gene Full Name	IKAROS family zinc finger 2
Gene Alias	ANF1A2; HELIOS; ZNF1A2; ZNFN1A2
Transcripts	ENSG00000030419
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q9UKS7
HGNC ID	HGNC:13177
VEGA ID	OTTHUMG00000133005
OMIM ID	606234
String ID	9606.ENSP00000412869
PharmGKB ID	PA162391927

Target gene [IKZF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003223	chr2	41	42	72	155	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of IKZF2 expression and immune infiltrating cell level correlation result in HBV+ samples
IKZF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).