HIV Target gene Detail Information

> IL10RB Gene Search Result

Gene Information

Gene Name	IL10RB
Gene ID	3588
Gene Full Name	interleukin 10 receptor subunit beta
Gene Alias	CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2
Transcripts	ENSG00000243646
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q08334
HGNC ID	HGNC:5965
VEGA ID	OTTHUMG00000065128
OMIM ID	123889
String ID	9606.ENSP00000290200
PharmGKB ID	PA29780

Target gene [IL10RB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005949	chr21	16	5	7	28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of IL10RB expression and immune infiltrating cell level correlation result in HIV+ samples
IL10RB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of IL10RB expression and immune infiltrating cell level correlation result in HIV+ samples
IL10RB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).