HBV Target gene Detail Information

> ITGAD Gene Search Result

Gene Information

Gene Name	ITGAD
Gene ID	3681
Gene Full Name	integrin subunit alpha D
Gene Alias	ADB2; CD11D
Transcripts	ENSG00000156886
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins
Uniport_ID	Q13349
HGNC ID	HGNC:6146
VEGA ID	OTTHUMG00000176614
OMIM ID	602453
String ID	9606.ENSP00000373854
PharmGKB ID	PA29946

Target gene [ITGAD] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001017	chr16	1011	102	44	1157	View
1001917	chr16	251	90	91	432	View
1001918	chr16	251	90	91	432	View
1004478	chr16	42	33	6	81	View
1004841	chr16	58	10		68	View
1007175	chr16	24	6		30	View
1008641	chr16	3	15	2	20	View
1009712	chr16	8	6	1	15	View
1011147	chr16	6	4		10	View
1011148	chr16	6	4		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITGAD expression and immune infiltrating cell level correlation result in HBV+ samples
ITGAD expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).