HBV Target gene Detail Information

> ITGAM Gene Search Result

Gene Information

Gene Name	ITGAM
Gene ID	3684
Gene Full Name	integrin subunit alpha M
Gene Alias	CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
Transcripts	ENSG00000169896
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P11215
HGNC ID	HGNC:6149
VEGA ID	OTTHUMG00000176612
OMIM ID	120980
String ID	9606.ENSP00000441691
PharmGKB ID	PA29949

Target gene [ITGAM] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004822	chr16	66	2		68	View
1011281	chr16	5	4		9	View
1402531	chr16	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ITGAM expression and immune infiltrating cell level correlation result in HBV+ samples
ITGAM expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).