HBV Target gene Detail Information

> KDM4C Gene Search Result

Gene Information

Gene Name	KDM4C
Gene ID	23081
Gene Full Name	lysine demethylase 4C
Gene Alias	GASC1; JHDM3C; JMJD2C; TDRD14C
Transcripts	ENSG00000107077
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9H3R0
HGNC ID	HGNC:17071
VEGA ID	OTTHUMG00000019536
OMIM ID	605469
PharmGKB ID	PA164721503

Target gene [KDM4C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002051	chr9	323	34	4	361	View
1007290	chr9	18	10		28	View
1007667	chr9	21	4		25	View
1009051	chr9	17	1		18	View
1011635	chr9	4	4		8	View
1401843	chr9	4	4		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KDM4C expression and immune infiltrating cell level correlation result in HBV+ samples
KDM4C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).