HIV Target gene Detail Information

> KDM5A Gene Search Result

Gene Information

Gene Name	KDM5A
Gene ID	5927
Gene Full Name	lysine demethylase 5A
Gene Alias	RBP2; RBBP2; RBBP-2
Transcripts	ENSG00000073614
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Cytosol;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P29375
HGNC ID	HGNC:9886
VEGA ID	OTTHUMG00000168055
OMIM ID	180202
String ID	9606.ENSP00000382688
PharmGKB ID	PA34250

Target gene [KDM5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005160	chr12	27	8		35	View
4009730	chr12	11			11	View
4009898	chr12	8	2		10	View
4013847	chr12	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KDM5A expression and immune infiltrating cell level correlation result in HIV+ samples
KDM5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).