HIV Target gene Detail Information

> KHDRBS1 Gene Search Result

Gene Information

Gene Name	KHDRBS1
Gene ID	10657
Gene Full Name	KH RNA binding domain containing, signal transduction associated 1
Gene Alias	p62; p68; Sam68
Transcripts	ENSG00000121774
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q07666
HGNC ID	HGNC:18116
VEGA ID	OTTHUMG00000003921
OMIM ID	602489
String ID	9606.ENSP00000313829
PharmGKB ID	PA30092

Target gene [KHDRBS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001669	chr1	96	33	13	142	View
4001897	chr1	82	9	33	124	View
4007585	chr1	18			18	View
4012556	chr1	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KHDRBS1 expression and immune infiltrating cell level correlation result in HIV+ samples
KHDRBS1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KHDRBS1 expression and immune infiltrating cell level correlation result in HIV+ samples
KHDRBS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).