HTLV1 Target gene Detail Information

> KRT80 Gene Search Result

Gene Information

Gene Name	KRT80
Gene ID	144501
Gene Full Name	keratin 80
Gene Alias	KB20
Transcripts	ENSG00000167767
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Intermediate filaments;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q6KB66
HGNC ID	HGNC:27056
VEGA ID	OTTHUMG00000150193
OMIM ID	611161
String ID	9606.ENSP00000378292
PharmGKB ID	PA147357831

Target gene [KRT80] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008690	chr12	21	21	1	43	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KRT80 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KRT80 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of KRT80 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KRT80 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).