HBV Target gene Detail Information

> MACROD2 Gene Search Result

Gene Information

Gene Name	MACROD2
Gene ID	140733
Gene Full Name	MACRO domain containing 2
Gene Alias	C2orf133; C20orf133
Transcripts	ENSG00000172264
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	A1Z1Q3
HGNC ID	HGNC:16126
VEGA ID	OTTHUMG00000031919
OMIM ID	611567
String ID	9606.ENSP00000217246
PharmGKB ID	PA162394843

Target gene [MACROD2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002028	chr20	277	60	32	369	View
1002667	chr20	204	13	9	226	View
1003990	chr20	15	56	27	98	View
1005114	chr20			61	61	View
1008878	chr20	10	4	5	19	View
1010711	chr20	8	3		11	View
1012317	chr20	2	1	4	7	View
1012318	chr20	2	1	4	7	View
1013403	chr20	4	1		5	View
1013479	chr20		3	2	5	View
1015403	chr20	2			2	View
1015404	chr20	2			2	View
1017373	chr20		1		1	View
1404668	chr20	13	15	36	64	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MACROD2 expression and immune infiltrating cell level correlation result in HBV+ samples
MACROD2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).