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HPV Target gene Detail Information

> MC3R Gene Search Result


Gene Information
Gene Name MC3R
Gene ID 4159
Gene Full Name melanocortin 3 receptor
Gene Alias MC3; OB20; OQTL; BMIQ9; MC3-R
Transcripts ENSG00000124089
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted membrane proteins
Uniport_ID P41968
HGNC ID HGNC:6931
VEGA ID OTTHUMG00000032785
OMIM ID 155540
String ID 9606.ENSP00000243911
Drugbank ID BE0009607
PharmGKB ID PA30675
Target gene [MC3R] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403084 chr20 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of MC3R expression and immune infiltrating cell level correlation result in HPV+ samples
MC3R expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of MC3R expression and immune infiltrating cell level correlation result in HPV+ samples
MC3R expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of MC3R expression and immune infiltrating cell level correlation result in HPV+ samples
MC3R expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of MC3R expression and immune infiltrating cell level correlation result in HPV+ samples
MC3R expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of MC3R expression and immune infiltrating cell level correlation result in HPV+ samples
MC3R expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).