HIV Target gene Detail Information

> MIOS Gene Search Result

Gene Information

Gene Name	MIOS
Gene ID	54468
Gene Full Name	meiosis regulator for oocyte development
Gene Alias	MIO; Sea4; Yulink
Transcripts	ENSG00000164654
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NXC5
HGNC ID	HGNC:21905
VEGA ID	OTTHUMG00000152440
OMIM ID	615359
String ID	9606.ENSP00000339881
PharmGKB ID	PA164722300

Target gene [MIOS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002993	chr7	53	10	11	74	View
4012004	chr7	2	3	1	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MIOS expression and immune infiltrating cell level correlation result in HIV+ samples
MIOS expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MIOS expression and immune infiltrating cell level correlation result in HIV+ samples
MIOS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).