HBV Target gene Detail Information

> MMACHC Gene Search Result

Gene Information

Gene Name	MMACHC
Gene ID	25974
Gene Full Name	metabolism of cobalamin associated C
Gene Alias	cblC
Transcripts	ENSG00000132763
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9Y4U1
HGNC ID	HGNC:24525
VEGA ID	OTTHUMG00000007742
OMIM ID	609831
String ID	9606.ENSP00000383840
Drugbank ID	BE0002175
PharmGKB ID	PA142671348

Target gene [MMACHC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004033	chr1	93	3		96	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MMACHC expression and immune infiltrating cell level correlation result in HBV+ samples
MMACHC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).