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HBV Target gene Detail Information

> MME Gene Search Result


Gene Information
Gene Name MME
Gene ID 4311
Gene Full Name membrane metalloendopeptidase
Gene Alias NEP; SFE; CD10; CALLA; CMT2T; SCA43
Transcripts ENSG00000196549
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID P08473
HGNC ID HGNC:7154
VEGA ID OTTHUMG00000158455
OMIM ID 120520
String ID 9606.ENSP00000418525
Drugbank ID BE0000266
PharmGKB ID PA30864
Target gene [MME] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003095 chr3 78 17 72 167 View
1003121 chr3 76 17 71 164 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MME expression and immune infiltrating cell level correlation result in HBV+ samples
MME expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).