HPV Target gene Detail Information

> MMP13 Gene Search Result

Gene Information

Gene Name	MMP13
Gene ID	4322
Gene Full Name	matrix metallopeptidase 13
Gene Alias	CLG3; MDST; MANDP1; MMP-13
Transcripts	ENSG00000137745
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID	P45452
HGNC ID	HGNC:7159
VEGA ID	OTTHUMG00000165850
OMIM ID	600108
String ID	9606.ENSP00000260302
Drugbank ID	BE0000966
PharmGKB ID	PA30871

Target gene [MMP13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5401089	chr11	1			1	View
5402929	chr11	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of MMP13 expression and immune infiltrating cell level correlation result in HPV+ samples
MMP13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).