HBV Target gene Detail Information

> MS4A12 Gene Search Result

Gene Information

Gene Name	MS4A12
Gene ID	54860
Gene Full Name	membrane spanning 4-domains A12
Gene Alias	Ms4a10
Transcripts	ENSG00000071203
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Endoplasmic reticulum;Golgi apparatus;Nucleoli;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9NXJ0
HGNC ID	HGNC:13370
VEGA ID	OTTHUMG00000165364
OMIM ID	606550
String ID	9606.ENSP00000016913
PharmGKB ID	PA134971353

Target gene [MS4A12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1400571	chr11	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MS4A12 expression and immune infiltrating cell level correlation result in HBV+ samples
MS4A12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).