HIV Target gene Detail Information

> MYH9 Gene Search Result

Gene Information

Gene Name	MYH9
Gene ID	4627
Gene Full Name	myosin heavy chain 9
Gene Alias	MHA; FTNS; EPSTS; BDPLT6; DFNA17; MATINS; NMMHCA; NMHC-II-A; NMMHC-IIA
Transcripts	ENSG00000100345
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Plasma membrane;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P35579
HGNC ID	HGNC:7579
VEGA ID	OTTHUMG00000030429
OMIM ID	160775
String ID	9606.ENSP00000216181
Drugbank ID	BE0009170
PharmGKB ID	PA31377

Target gene [MYH9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000557	chr22	20	240	112	372	View
4001617	chr22	117	7	22	146	View
4002618	chr22	29	25	33	87	View
4004059	chr22	41	9		50	View
4005803	chr22	9	18	2	29	View
4006649	chr22	6	15	2	23	View
4008615	chr22	10	2	2	14	View
4011744	chr22	6			6	View
4011964	chr22	6			6	View
4012484	chr22	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MYH9 expression and immune infiltrating cell level correlation result in HIV+ samples
MYH9 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MYH9 expression and immune infiltrating cell level correlation result in HIV+ samples
MYH9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).