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HBV Target gene Detail Information

> MYO3B Gene Search Result


Gene Information
Gene Name MYO3B
Gene ID 140469
Gene Full Name myosin IIIB
Transcripts ENSG00000071909
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q8WXR4
HGNC ID HGNC:15576
VEGA ID OTTHUMG00000154002
OMIM ID 610040
String ID 9606.ENSP00000386213
PharmGKB ID PA31406
Target gene [MYO3B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008097 chr2 16 5 1 22 View
1010899 chr2 10 10 View
1010900 chr2 10 10 View
1010901 chr2 10 10 View
1010902 chr2 10 10 View
1010903 chr2 10 10 View
1010904 chr2 10 10 View
1010905 chr2 10 10 View
1014679 chr2 2 1 3 View
1015537 chr2 2 2 View
1015538 chr2 2 2 View
1015539 chr2 2 2 View
1015540 chr2 2 2 View
1015541 chr2 2 2 View
1015672 chr2 2 2 View
1015761 chr2 2 2 View
1015762 chr2 2 2 View
1015820 chr2 2 2 View
1015833 chr2 2 2 View
1015834 chr2 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MYO3B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MYO3B expression: Low -> High
Lollipop of MYO3B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MYO3B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MYO3B expression and immune infiltrating cell level correlation result in HBV+ samples
MYO3B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).