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HPV Target gene Detail Information

> NLRP14 Gene Search Result


Gene Information
Gene Name NLRP14
Gene ID 338323
Gene Full Name NLR family pyrin domain containing 14
Gene Alias NOD5; PAN8; GC-LRR; NALP14; CLR11.2
Transcripts ENSG00000158077
Virus HPV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q86W24
HGNC ID HGNC:22939
VEGA ID OTTHUMG00000165508
OMIM ID 609665
String ID 9606.ENSP00000299481
PharmGKB ID PA162397917
Target gene [NLRP14] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002429 chr11 10 1 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of NLRP14 expression and immune infiltrating cell level correlation result in HPV+ samples
NLRP14 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).