HBV Target gene Detail Information

> NLRP5 Gene Search Result

Gene Information

Gene Name	NLRP5
Gene ID	126206
Gene Full Name	NLR family pyrin domain containing 5
Gene Alias	MATER; NALP5; PAN11; PYPAF8; CLR19.8
Transcripts	ENSG00000171487
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P59047
HGNC ID	HGNC:21269
VEGA ID	OTTHUMG00000149887
OMIM ID	609658
String ID	9606.ENSP00000375063
PharmGKB ID	PA162397970

Target gene [NLRP5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015339	chr19	1	1		2	View
1400858	chr19	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NLRP5 expression and immune infiltrating cell level correlation result in HBV+ samples
NLRP5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).