HIV Target gene Detail Information

> NSF Gene Search Result

Gene Information

Gene Name	NSF
Gene ID	4905
Gene Full Name	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Gene Alias	SKD2; SEC18
Transcripts	ENSG00000276262
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Transporters
Uniport_ID	P46459
HGNC ID	HGNC:8016
VEGA ID	OTTHUMG00000190437
OMIM ID	601633
String ID	9606.ENSP00000381293
Drugbank ID	BE0004508
PharmGKB ID	PA31793

Target gene [NSF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001338	chr17	11	129	36	176	View
4015061	chr17			1	1	View
4015744	chr17	1			1	View
4015922	chr17				0	View
4016247	chr17				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NSF expression and immune infiltrating cell level correlation result in HIV+ samples
NSF expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NSF expression and immune infiltrating cell level correlation result in HIV+ samples
NSF expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).