HBV Target gene Detail Information

> NT5E Gene Search Result

Gene Information

Gene Name	NT5E
Gene ID	4907
Gene Full Name	5'-nucleotidase ecto
Gene Alias	NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA
Transcripts	ENSG00000135318
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P21589
HGNC ID	HGNC:8021
VEGA ID	OTTHUMG00000015139
OMIM ID	129190
String ID	9606.ENSP00000257770
Drugbank ID	BE0001096
PharmGKB ID	PA31804

Target gene [NT5E] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001773	chr6	430	31	27	488	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NT5E expression and immune infiltrating cell level correlation result in HBV+ samples
NT5E expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).