HIV Target gene Detail Information

> NUCB2 Gene Search Result

Gene Information

Gene Name	NUCB2
Gene ID	4925
Gene Full Name	nucleobindin 2
Gene Alias	NEFA; HEL-S-109
Transcripts	ENSG00000070081
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
HGNC ID	HGNC:8044
VEGA ID	OTTHUMG00000166050
OMIM ID	608020
String ID	9606.ENSP00000436455
Drugbank ID	BE0008838; BE0008701
PharmGKB ID	PA31826

Target gene [NUCB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008995	chr11	8	4	1	13	View
4014817	chr11	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NUCB2 expression and immune infiltrating cell level correlation result in HIV+ samples
NUCB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NUCB2 expression and immune infiltrating cell level correlation result in HIV+ samples
NUCB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).