HBV Target gene Detail Information

> OPA1 Gene Search Result

Gene Information

Gene Name	OPA1
Gene ID	4976
Gene Full Name	OPA1, mitochondrial dynamin like GTPase
Gene Alias	NPG; NTG; MGM1; BERHS; largeG; MTDPS14
Transcripts	ENSG00000198836
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O60313
HGNC ID	HGNC:8140
VEGA ID	OTTHUMG00000149897
OMIM ID	605290
String ID	9606.ENSP00000354681
PharmGKB ID	PA31927

Target gene [OPA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006232	chr3	34	7		41	View
1007110	chr3	25	5		30	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of OPA1 expression and immune infiltrating cell level correlation result in HBV+ samples
OPA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).