HBV Target gene Detail Information

> OPRK1 Gene Search Result

Gene Information

Gene Name	OPRK1
Gene ID	4986
Gene Full Name	opioid receptor kappa 1
Gene Alias	KOR; OPRK; KOR-1; K-OR-1
Transcripts	ENSG00000082556
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P41145
HGNC ID	HGNC:8154
VEGA ID	OTTHUMG00000164276
OMIM ID	165196
String ID	9606.ENSP00000265572
Drugbank ID	BE0000632
PharmGKB ID	PA31943

Target gene [OPRK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008026	chr8	1	22		23	View
1400337	chr8	122	18		140	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of OPRK1 expression and immune infiltrating cell level correlation result in HBV+ samples
OPRK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).