HIV Target gene Detail Information

> PDE6G Gene Search Result

Gene Information

Gene Name	PDE6G
Gene ID	5148
Gene Full Name	phosphodiesterase 6G
Gene Alias	PDEG; RP57
Transcripts	ENSG00000185527
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P18545
HGNC ID	HGNC:8789
VEGA ID	OTTHUMG00000178038
OMIM ID	180073
String ID	9606.ENSP00000328412
Drugbank ID	BE0003556
PharmGKB ID	PA33137

Target gene [PDE6G] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000372	chr17	161	181	165	507	View
4016252	chr17				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDE6G expression and immune infiltrating cell level correlation result in HIV+ samples
PDE6G expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).