HBV Target gene Detail Information

> PDXK Gene Search Result

Gene Information

Gene Name	PDXK
Gene ID	8566
Gene Alias	PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124
Transcripts	ENSG00000160209
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	O00764
HGNC ID	HGNC:8819
VEGA ID	OTTHUMG00000086870
OMIM ID	179020
String ID	9606.ENSP00000291565
Drugbank ID	BE0000042
PharmGKB ID	PA33162

Target gene [PDXK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000355	chr21	1507	677	475	2659	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PDXK expression and immune infiltrating cell level correlation result in HBV+ samples
PDXK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).