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HPV Target gene Detail Information

> PGAP3 Gene Search Result


Gene Information
Gene Name PGAP3
Gene ID 93210
Gene Full Name post-GPI attachment to proteins 3
Gene Alias CAB2; PERLD1; PP1498; hCOS16; AGLA546
Transcripts ENSG00000161395
Virus HPV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q96FM1
HGNC ID HGNC:23719
VEGA ID OTTHUMG00000179110
OMIM ID 611801
String ID 9606.ENSP00000300658
PharmGKB ID PA165432310
Target gene [PGAP3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5300431 chr17 6 5 2 13 View
5402830 chr17 6 5 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of PGAP3 expression and immune infiltrating cell level correlation result in HPV+ samples
PGAP3 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of PGAP3 expression and immune infiltrating cell level correlation result in HPV+ samples
PGAP3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).