Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> PIK3CG Gene Search Result


Gene Information
Gene Name PIK3CG
Gene ID 5294
Gene Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Gene Alias PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
Transcripts ENSG00000105851
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Cytosol;
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID P48736
HGNC ID HGNC:8978
VEGA ID OTTHUMG00000157641
OMIM ID 601232
String ID 9606.ENSP00000352121
Drugbank ID BE0001315
Drug (Cytoscape Annotation) Idelalisib
PharmGKB ID PA33311
FDA Approved Drug Duvelisib
Target gene [PIK3CG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007768 chr7 12 9 3 24 View
1402822 chr7 12 9 3 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PIK3CG expression and immune infiltrating cell level correlation result in HBV+ samples
PIK3CG expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).