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HPV Target gene Detail Information

> PLAC1 Gene Search Result


Gene Information
Gene Name PLAC1
Gene ID 10761
Gene Full Name placenta specific 1
Gene Alias CT92; OOSP2B; OOSP2L
Transcripts ENSG00000170965
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted secreted proteins
Uniport_ID Q9HBJ0
HGNC ID HGNC:9044
VEGA ID OTTHUMG00000022457
OMIM ID 300296
String ID 9606.ENSP00000352173
PharmGKB ID PA33371
Target gene [PLAC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000331 chrX 21 134 143 298 View
5003839 chrX 2 2 View
5201113 chrX 13 1 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of PLAC1 expression and immune infiltrating cell level correlation result in HPV+ samples
PLAC1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).