HIV Target gene Detail Information

> POU2AF1 Gene Search Result

Gene Information

Gene Name	POU2AF1
Gene ID	5450
Gene Full Name	POU class 2 associating factor 1
Gene Alias	BOB1; OBF1; OCAB; OBF-1
Transcripts	ENSG00000110777
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q16633
HGNC ID	HGNC:9211
VEGA ID	OTTHUMG00000166659
OMIM ID	601206
String ID	9606.ENSP00000376786
PharmGKB ID	PA33535

Target gene [POU2AF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003747	chr11	52	3		55	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of POU2AF1 expression and immune infiltrating cell level correlation result in HIV+ samples
POU2AF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).