HBV Target gene Detail Information

> PPIL6 Gene Search Result

Gene Information

Gene Name	PPIL6
Gene ID	285755
Gene Full Name	peptidylprolyl isomerase like 6
Gene Alias	PPIase; RSPH12; bA425D10.6; dJ919F19.1
Transcripts	ENSG00000185250
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Golgi apparatus;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8IXY8
HGNC ID	HGNC:21557
VEGA ID	OTTHUMG00000036593
String ID	9606.ENSP00000392257
PharmGKB ID	PA134939571

Target gene [PPIL6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010315	chr6	6	2	4	12	View
1403858	chr6	6	2	4	12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PPIL6 expression and immune infiltrating cell level correlation result in HBV+ samples
PPIL6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).