HIV Target gene Detail Information

> PPP3CB Gene Search Result

Gene Information

Gene Name	PPP3CB
Gene ID	5532
Gene Full Name	protein phosphatase 3 catalytic subunit beta
Gene Alias	CNA2; CALNB; CALNA2; PP2Bbeta
Transcripts	ENSG00000107758
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	P16298
HGNC ID	HGNC:9315
VEGA ID	OTTHUMG00000018472
OMIM ID	114106
String ID	9606.ENSP00000378306
PharmGKB ID	PA33679

Target gene [PPP3CB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006218	chr10	24	2		26	View
4006734	chr10	23			23	View
4006858	chr10	22			22	View
4013077	chr10	1	2	1	4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP3CB expression and immune infiltrating cell level correlation result in HIV+ samples
PPP3CB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP3CB expression and immune infiltrating cell level correlation result in HIV+ samples
PPP3CB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).