HIV Target gene Detail Information

> PTTG1IP Gene Search Result

Gene Information

Gene Name	PTTG1IP
Gene ID	754
Gene Full Name	PTTG1 interacting protein
Gene Alias	PBF; C21orf1; C21orf3
Transcripts	ENSG00000183255
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P53801
HGNC ID	HGNC:13524
VEGA ID	OTTHUMG00000090254
OMIM ID	603784
String ID	9606.ENSP00000328325
PharmGKB ID	PA34034

Target gene [PTTG1IP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000494	chr21	154	222	54	430	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTTG1IP expression and immune infiltrating cell level correlation result in HIV+ samples
PTTG1IP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTTG1IP expression and immune infiltrating cell level correlation result in HIV+ samples
PTTG1IP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).