HIV Target gene Detail Information

> RAG1 Gene Search Result

Gene Information

Gene Name	RAG1
Gene ID	5896
Gene Full Name	recombination activating 1
Gene Alias	RAG-1; RNF74
Transcripts	ENSG00000166349
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P15918
HGNC ID	HGNC:9831
VEGA ID	OTTHUMG00000166392
OMIM ID	179615
String ID	9606.ENSP00000299440
PharmGKB ID	PA34185

Target gene [RAG1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000650	chr8	176	53	108	337	View
4000884	chr8	105	43	108	256	View
4014594	chr11		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAG1 expression and immune infiltrating cell level correlation result in HIV+ samples
RAG1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).