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HBV Target gene Detail Information

> RARA Gene Search Result


Gene Information
Gene Name RARA
Gene ID 5914
Gene Full Name retinoic acid receptor alpha
Gene Alias RAR; NR1B1
Transcripts ENSG00000131759
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Actin filaments;Cytosol;Nucleoli;
HPA Protein Class Info Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID P10276
HGNC ID HGNC:9864
VEGA ID OTTHUMG00000133328
OMIM ID 180240
String ID 9606.ENSP00000254066
Drugbank ID BE0000663
Drug (Cytoscape Annotation) Bexarotene
PharmGKB ID PA34225
Target gene [RARA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004301 chr17 44 11 31 86 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RARA expression and immune infiltrating cell level correlation result in HBV+ samples
RARA expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).