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HTLV1 Target gene Detail Information

> REN Gene Search Result


Gene Information
Gene Name REN
Gene ID 5972
Gene Full Name renin
Gene Alias HNFJ2
Transcripts ENSG00000143839
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P00797
HGNC ID HGNC:9958
VEGA ID OTTHUMG00000036059
OMIM ID 179820
String ID 9606.ENSP00000272190
Drugbank ID BE0000270
PharmGKB ID PA297
Target gene [REN] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010047 chr7 29 4 33 View
6019406 chr1 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of REN expression and immune infiltrating cell level correlation result in HTLV1+ samples
REN expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of REN expression and immune infiltrating cell level correlation result in HTLV1+ samples
REN expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of REN expression and immune infiltrating cell level correlation result in HTLV1+ samples
REN expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).