HTLV1 Target gene Detail Information

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Gene Information

Gene Name	RET
Gene ID	5979
Gene Full Name	ret proto-oncogene
Gene Alias	PTC; MTC1; HSCR1; MEN2A; MEN2B; CDHF12; CDHR16; RET-ELE1
Transcripts	ENSG00000165731
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P07949
HGNC ID	HGNC:9967
VEGA ID	OTTHUMG00000018024
OMIM ID	164761
String ID	9606.ENSP00000347942
Drugbank ID	BE0001104; BE0002411
PharmGKB ID	PA34335
FDA Approved Drug	Cabozantinib;Pralsetinib;Selpercatinib

Target gene [RET] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6016661	chr10	10	1	1	12	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).