EBV Target gene Detail Information

> RNF112 Gene Search Result

Gene Information

Gene Name	RNF112
Gene ID	7732
Gene Full Name	ring finger protein 112
Gene Alias	BFP; ZNF179
Transcripts	ENSG00000128482
Virus	EBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9ULX5
HGNC ID	HGNC:12968
VEGA ID	OTTHUMG00000059601
OMIM ID	601237
String ID	9606.ENSP00000454919
PharmGKB ID	PA162401469

Target gene [RNF112] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3200052	chr17	122	79	11	212	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE45919 (GEO)	Infectious mononucleosis	24	Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO)	Multiple sclerosis	32	Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE45919
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE58240
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of RNF112 expression and immune infiltrating cell level correlation result in EBV+ samples
RNF112 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: GSE102203