HTLV1 Target gene Detail Information

> ROS1 Gene Search Result

Gene Information

Gene Name	ROS1
Gene ID	6098
Gene Full Name	ROS proto-oncogene 1, receptor tyrosine kinase
Gene Alias	ROS; MCF3; c-ros-1
Transcripts	ENSG00000047936
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P08922
HGNC ID	HGNC:10261
VEGA ID	OTTHUMG00000016188
OMIM ID	165020
String ID	9606.ENSP00000357494
Drugbank ID	BE0009488; BE0009534
PharmGKB ID	PA34633
FDA Approved Drug	Entrectinib;Crizotinib;Lorlatinib

Target gene [ROS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000152	chr3	2776	343	597	3716	View
6000594	chr3	978	81	106	1165	View
6000677	chr3	861	64	76	1001	View
6001604	chr6	26	341	20	387	View
6001715	chr6	46	194	121	361	View
6005859	chr3	55	22	2	79	View
6011087	chr3	4	12	12	28	View
6011515	chr3	5	19	2	26	View
6011516	chr3	5	19	2	26	View
6011517	chr3	5	19	2	26	View
6027637	chr3	1	1		2	View
6027932	chr3		1		1	View
6029955	chr6	1			1	View
6030462	chr6				0	View
6030607	chr6				0	View
6033505	chr6				0	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).