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HPV Target gene Detail Information

> RPRM Gene Search Result


Gene Information
Gene Name RPRM
Gene ID 56475
Gene Full Name reprimo, TP53 dependent G2 arrest mediator homolog
Gene Alias REPRIMO
Transcripts ENSG00000177519
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q9NS64
HGNC ID HGNC:24201
VEGA ID OTTHUMG00000131905
OMIM ID 612171
String ID 9606.ENSP00000314946
PharmGKB ID PA134937494
Target gene [RPRM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5200600 chr2 19 1 1 21 View
5201853 chr2 1 1 View
5403706 chr2 1 1 2 View
5404186 chr2 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of RPRM expression and immune infiltrating cell level correlation result in HPV+ samples
RPRM expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).