HPV Target gene Detail Information

> RSPH4A Gene Search Result


Gene Information
Gene Name RSPH4A
Gene ID 345895
Gene Full Name radial spoke head component 4A
Gene Alias RSHL3; CILD11; RSPH6B; dJ412I7.1
Transcripts ENSG00000111834
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q5TD94
HGNC ID HGNC:21558
VEGA ID OTTHUMG00000015444
OMIM ID 612647
String ID 9606.ENSP00000229554
PharmGKB ID PA164725568
Target gene [RSPH4A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5001493 chr6 29 2 31 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of RSPH4A expression and immune infiltrating cell level correlation result in HPV+ samples
RSPH4A expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of RSPH4A expression and immune infiltrating cell level correlation result in HPV+ samples
RSPH4A expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of RSPH4A expression and immune infiltrating cell level correlation result in HPV+ samples
RSPH4A expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of RSPH4A expression and immune infiltrating cell level correlation result in HPV+ samples
RSPH4A expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of RSPH4A expression and immune infiltrating cell level correlation result in HPV+ samples
RSPH4A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).